# HALO® Columns for Chromatography Separations: Fused\-Core® Technology

> HALO® is a leader in high performance liquid chromatography columns\. Improve efficiency and analyze faster with our HPLC columns\.

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## Pages
- [Find a Distributor](https://halocolumns.com/find-a-distributor/)
- [What's New](https://halocolumns.com/new-products/)
- [What's New](https://halocolumns.com/whats-new/)
- [Home](https://halocolumns.com/)
- [Introducing HALO® Elevate](https://halocolumns.com/halo-elevate/)

## Posts
- [Improved LC and LC\-MS Separations of Oligonucleotides Using Superficially Porous Particles](https://halocolumns.com/improved-lc-and-lc-ms-separations-of-oligonucleotides/)
- [HALO® at Pittcon 2026](https://halocolumns.com/halo-at-pittcon-2026/)
- [AMT Connection Highlighted at Pittcon 2026 Award Session](https://halocolumns.com/amt-connection-highlighted-at-pittcon-2026-award-session/)
- [The Chromatographic Impact of Hydrophobic and Steric Modifications in siRNAs](https://halocolumns.com/the-chromatographic-impact-of-hydrophobic-and-steric-modifications-in-sirnas/)
- [HALO® at HPLC 2026](https://halocolumns.com/halo-at-hplc-2026/)

## Application Notes
- [Advantage of HALO ELEVATE Loading Capability: High vs\. Low pH](https://halocolumns.com/application-notes/advantage-of-halo-elevate-loading-capability-high-vs-low-ph/)
- [Drugs of Abuse Selectivity on HALO ELEVATE Phases: C18 and Phenyl\-Hexyl](https://halocolumns.com/application-notes/drugs-of-abuse-selectivity-on-halo-elevate-phases-c18-and-phenyl-hexyl/)
- [HALO ELEVATE C18 Demonstrating Advantage of Fused\-Core with Increased Flow Rate](https://halocolumns.com/application-notes/halo-elevate-c18-demonstrating-advantage-of-fused-core-with-increased-flow-rate/)
- [Separation of Antidepressants\-HALO® ELEVATE Phenyl\-Hexyl vs\. FPP Phenyl Phase](https://halocolumns.com/application-notes/separation-of-antidepressants-halo-elevate-phenyl-hexyl-vs-fpp-phenyl-phase/)
- [HALO®ELEVATE Advantage for High pH Analysis on Cocaine Metabolites](https://halocolumns.com/application-notes/haloelevate-advantage-for-high-ph-analysis-on-cocaine-metabolites/)

## Conference Papers
- [Improved HPLC Method Development Using Wide pH Range](https://halocolumns.com/conference-papers/improved-hplc-method-development-using-wide-ph-range/)
- [Assessment of Stationary Phase Ligands on Positively Charged Particles by Anionic Exchange Parameter](https://halocolumns.com/conference-papers/assessment-of-stationary-phase-ligands-on-positively-charged-particles-by-anionic-exchange-parameter/)
- [Sharper Peaks and Higher Sensitivity: Advancing Positively Charged Surface Stationary Phase Technology with 2µm Particles](https://halocolumns.com/conference-papers/sharper-peaks-and-higher-sensitivity-advancing-positively-charged-surface-stationary-phase-technology-with-2µm-particles/)
- [Selectivity and Efficiency Effects of Pore Size on Hybrid SPP on Nucleic Acids Separations](https://halocolumns.com/conference-papers/selectivity-and-efficiency-effects-of-pore-size-on-hybrid-spp-on-nucleic-acids-separations/)
- [Advanced SPP Separations Materials for LC/MS Analyses of Synthetic Oligonucleotides](https://halocolumns.com/conference-papers/advanced-spp-separations-materials-for-lc-ms-analyses-of-synthetic-oligonucleotides/)

## Product Literature
- [ELEVATE Brochure](https://halocolumns.com/product-literature/elevate-brochure/)
- [HALO® OLIGO Guidebook](https://halocolumns.com/product-literature/halo-oligo-guidebook/)
- [BIOCLASS Catalog](https://halocolumns.com/product-literature/bioclass-catalog/)
- [AQ\-C18 Brochure](https://halocolumns.com/product-literature/aq-c18-brochure-2/)
- [HILIC Solutions Brochure](https://halocolumns.com/product-literature/hilic-solutions-brochure/)

## Technical Documents
- [LC\-MS/MS SCREENING OF NITROSAMINES USING HALO® COLUMNS](https://halocolumns.com/technical-document/lc-ms-ms-screening-of-nitrosamines-using-halo-columns/)
- [Under the HALO®: Importance of HPLC Mobile Phase Additives/ Buffers](https://halocolumns.com/technical-document/under-the-halo-importance-of-hplc-mobile-phase-additives-buffers/)
- [Improved Retention of Ethanol Metabolites Ethyl Glucuronide and Ethyl Sulfate Using a Positively Charged Stationary Phase Under Low Ionic Strength Conditions](https://halocolumns.com/technical-document/improved-retention-of-ethanol-metabolites-ethyl-glucuronide-and-ethyl-sulfate-using-a-positively-charged-stationary-phase-under-low-ionic-strength-conditionsh/)
- [Importance of Proper HPLC Column Storage](https://halocolumns.com/technical-document/importance-of-proper-hplc-column-storage/)
- [HALO® Resolution, Sensitivity And Stability For Method Screening](https://halocolumns.com/technical-document/halo-resolution-sensitivity-and-stability-for-method-screening/)

## Videos
- [Webinar: Improve Your USP LC Gradient Separation Methods Following the New Guidelines](https://halocolumns.com/videos/webinar-improve-your-usp-lc-gradient-separation-methods-following-the-new-guidelines/)
- [Webinar: Reversed Phase Liquid Chromatography: Fundamentals and Strategies for Faster Method Development](https://halocolumns.com/videos/reversed-phase-liquid-chromatography-fundamentals-and-strategies-for-faster-method-development/)
- [Webinar: LC Separations and Workflow Improvements for Environmental and Food Safety](https://halocolumns.com/videos/lc-separations-and-workflow-improvements-for-environmental-and-food-safety/)
- [HALO® Extra Column Volume](https://halocolumns.com/videos/halo-extra-column-volume/)
- [AMT Company Video](https://halocolumns.com/videos/amt-company-video/)

## Testimonials
- [Customer Comment](https://halocolumns.com/testimonial/customer-comment/)
- [R\&D Scientist, Pharmaceutical](https://halocolumns.com/testimonial/rd-scientist-pharmaceutical/)
- [Chemical Analysis Group at Global CRO](https://halocolumns.com/testimonial/chemical-analysis-group-at-global-cro/)

## Products
- [HALO 120 Å ELEVATE C8](https://halocolumns.com/product/halo-120-a-elevate-c8/)
- [HALO 120 Å ELEVATE Phenyl\-Hexyl](https://halocolumns.com/product/halo-120-a-elevate-phenyl-hexyl/)
- [HALO 120 Å ELEVATE C18](https://halocolumns.com/product/halo-120-a-elevate-c18/)
- [HALO 160 Å PCS C18](https://halocolumns.com/product/halo-160-a-pcs-c18/)
- [HALO 1000 Å OLIGO C18](https://halocolumns.com/product/halo-1000-a-oligo-c18/)

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- [OLIGO Promotion](https://halocolumns.com/?post_type=popup&p=14577)
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