ADVANCED MATERIALS TECHNOLOGY
QUALITY FOCUSED, CUSTOMER DRIVEN
- ISO 9001 Certified
- Customer-focused processes and procedures
- Stage Gate process for Development Cycle
- Engineering for Long-Term Reliability and Performance
- Continuous improvement throughout our 20-year history
Structured Development
Our Stage Gate process ensures customer requirements are met from concept to completion.
Rigorous Testing
Each stage requires specific quality tests before advancing from R&D to Engineering to Manufacturing.
Consistent Quality
Our standardized process ensures collaboration and robust decision-making regardless of product complexity.
MAKING OF A HALO® PARTICLE
AMT has revolutionized chromatographic separations with the Fused-Core® particle technology.
Unlike competitors who utilize intermediates in their production, we control the entire manufacturing process from starting raw materials through finished columns.
With over 200+ quality checks throughout production, HALO® HPLC columns deliver industry-leading consistency, and high chromatographic efficiencies without the backpressure consequence.
Join us on the journey of engineering HALO® columns…
STARTING WITH
QUALITY RAW MATERIALS
We begin with three high purity raw materials, add energy and engineering to create the HALO® Fused-Core® particle
Core Creation
The foundation of the Fused-Core® particle
HALO® particles are silica based and begin with a spherical core.
The core is responsible for the reduction in diffusion path which leads to more analyte to bonded phase interactions creating high efficiencies.
20 Years of measuring Mean Particle Size:
RSD of < 0.08%
Quality
Testing
Tests
Coating
Building the Shell
Silica nanoparticles (1/10,000th thickness of a human hair!) are coated onto the core to create the shell.
AMT’s precise process ensures batch to batch consistency in pore size and shell thickness. This results in tight, industry-leading, particle size distributions.
Surface Area
Highly reproducible retention resulting from excellent control of surface area.
Particle Size Distribution
The narrow particle size distributions from the tightly controlled coating process allow for highly stable column beds.
Quality
Testing
14+
23+
55+
47+
94+
100+
in-process controls
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QC/QA
Tests
Finishing
SURFACE OPTIMIZATION
AMT uses a proprietary method to create uniform and consistent surface silanols. The particle is now ready for bonding or use.
AMT uses a challenging test at neutral pH with a basic analyte to confirm the uniformity of the surface silanols.
Bonding
Adding Chemistry
The silica particle is now perfectly sized and ready to be functionalized.
Temperature, humidity, and reaction times are precisely controlled as we functionalize the surface with different ligands such as C18 or Biphenyl.
Every bonded batch undergoes rigorous QA testing under multiple conditions to verify retention, selectivity, and peak shape to ensure the results achieved today will be reliable tomorrow and years from now.
Quality
Testing
Performance-based application testing performed on every batch
Lot to Lot reproducibility is a critical factor in quality. Typical result of % RSD over multiple bondingsis < 0.3%!
Column Loading
Final Assembly
The journey culminates as our perfectly sized, chemically optimized Fused-Core® particles are packed into stainless steel tubes under precisely controlled high pressure.
Our automated process ensures consistent density and eliminates variation in packing quality.
Optimized frit porosities and end fittings are applied where the finished column moves on to final QC testing.
Quality
Testing
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in-process controls
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QC/QA
Tests
Testing and Packaging
Quality in Delivery
Before any HALO® column leaves our facility, it undergoes comprehensive performance testing. Every AMT column ships with its own test chromatogram, verifying it meets our exacting standards.
This isn’t just quality control—it’s our brand promise.
Beyond Manufacturing Excellence
Fast Shipping & Continued Support
Our commitment to quality extends beyond manufacturing:
- 99% on-time delivery worldwide for over a decade
- 24 hour order processing on analytical columns
- Each column includes a quality verification chromatogram
and care and use sheet - Recyclable, environmentally-friendly packaging
- Dedicated technical support from experienced scientists
