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New Dimension in Chromatography - Halo® 1.5

MEET THE NEW HALO® 1.5

WE’RE TAKING
SEPARATIONS TO
A NEW DIMENSION

DOWNLOAD BROCHURE

The New HALO® 1.5 – Defining a New Dimension in Chromatography

The adoption of UHPLC instrumentation pushed LC separations to a new level of speed and resolution.  In the years since, chromatographers continue to push separation limits in response to increasing challenges.

How can I improve my separation in a faster time, or with less solvent consumption, increased sensitivity, or all of the above?  While the specific drivers may be different, the overall goal is the same – “I need more, but without sacrificing anything”.

 

Delivering More Performance

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More Sensitivity from conventional UHPLC Systems

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Higher Ionization Efficiencies from LCMS systems

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Reduce Solvent Consumption compared to 2.1 mm ID columns

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Easy to Implement microflow solution

More Sensitivity

  • Increased detector signal response from UHPLC and LCMS systems
  • >2x peak areas compared to 2.1 mm (and larger) id columns
  • Higher efficiencies compared to 1 mm id columns on UHPLC systems

Reduced & Alkylated mAb Shows >2x Signal Intensity

Comparison of New 1.5 mm vs 2.1 mm ID for OTC Cough & Cold Medicines

*see brochure for full test conditions

Solvent Reduction

  • Reduced internal diameter leads to lower optimal flow rates reducing solvent consumption
  • Decreased solvent waste removal costs
  • Less environmental impact

Peptide Map Solvent Savings Using HALO 160 Å ES-C18 in 1.5 mm ID

*see brochure for full test conditions

Stability

  • New 1.5 mm id hardware demonstrated excellent lot to lot reproducibility
  • Stability testing delivers RSD’s <0.3% with no loss in efficiency or retention
  • Manufactured in Advanced Materials Technology’s ISO 9001 certified facility

Stability of 1000 Injections on HALO 90 Å C18 in 1.5 mm ID

Excellent Lot to Lot Reproducibility

*see brochure for full test conditions

System Optimization

  • System optimization helps to ensure the best performance
  • Reducing UHPLC system contributors to extra column diffusion further enhances performance
  • Connection tubing is a large contributor to dispersion and can be easily exchanged for volume reduction
  • The use of MarvelXACT® finger-tight UHPLC connectors with volume definitions easily identifies the connection tubing volume contribution and ensures zero dead volume

Impact of Extra Column Dispersion on Column ID’s Using an Optimized UHPLC System

Featured Documents

Products Available in 1.5 mm

SMALL MOLECULE

HALO 90 Å C18

9281X-402HALO 90 A C18, 2.7 µm, 1.5 x 50 mm1.5 x 50 mmAdd to Cart
9281X-702HALO 90 A C18, 2.7 µm, 1.5 x 150 mm1.5 x 150 mmAdd to Cart
9281X-602HALO 90 A C18, 2.7 µm, 1.5 x 100 mm1.5 x 100 mmAdd to Cart

PEPTIDE

HALO 160 Å ES-C18

9212X-402HALO 160 A ES-C18, 2.7 µm, 1.5 x 50 mm1.5 x 50 mmAdd to Cart
9212X-602HALO 160 A ES-C18, 2.7 µm, 1.5 x 100 mm1.5 x 100 mmAdd to Cart
9212X-702HALO 160 A ES-C18, 2.7 µm, 1.5 x 150 mm1.5 x 150 mmAdd to Cart

PROTEIN

HALO 1000 Å DIPHENYL

9271X-426HALO 1000 A Diphenyl, 2.7 µm, 1.5 x 50 mm1.5 x 50 mmAdd to Cart
9271X-626HALO 1000 A Diphenyl, 2.7 µm, 1.5 x 100 mm1.5 x 100 mmAdd to Cart
9271X-726 HALO 1000 A Diphenyl, 2.7 µm, 1.5 x 150 mm1.5 x 150 mmAdd to Cart

HALO 1000 Å C4

9271X-414 HALO 1000 A C4, 2.7 µm, 1.5 x 50 mm1.5 x 50 mmAdd to Cart
9271X-614HALO 1000 A C4, 2.7 µm, 1.5 x 100 mm1.5 x 100 mmAdd to Cart
9271X-714HALO 1000 A C4, 2.7 µm, 1.5 x 150 mm1.5 x 150 mmAdd to Cart

HARDWARE & ACCESSORIES

ENSURE A PERFECT CONNECTION WITH MarvelXACT™

MarvelXACT™ connection systems have been designed to eliminate the risk of under- or over-tightening with a patented torque limiting mechanism. This unique feature emits a haptic “click” feedback when it reaches the optimum torque, assuring a perfect installation every time. MarvelXACT™ incorporates advanced MarvelX™ Sealing Technology to deliver precise face sealing (sealing at the port bottom), which eliminates additional internal volume, and minimizes carryover risk, peak tailing, and peak broadening.

MarvelXACT and MarvelX are registered trademarks of IDEX

AMT MarvelXACT™ Connection Tubing

$165.00$335.00

Clear

Description

  • Advanced Materials Technology’s MarvelXACT® finger-tight UHPLC connectors with volume definitions easily identifies dispersion volume contribution
  • Haptic “click” indicates optimum torque and zero dead volume connection
  • Connector and tubing for both pre and post column installation
  • Available in both PEEKsil® and PEEK lined stainless steel materials

MarvelXACT and MarvelX are registered trademarks of IDEX

  • Finger-tight connection up to 19,000 psi (~1310 bar)
  • 1/32” OD tubing
  • PEEKsil® and PEEK lined stainless steel
  • Available in id’s of 25 µm, 50 µm, 75 µm, and 100 µm
  • Available in lengths of 150 mm, 350mm, and 600 mm

HALO® 1.5 Patent Pending Design

Questions? Let's Talk Chromatography!

taking advantage of fused-core® technology

Visit our solutions pages to learn more about the best uses and benefits of Fused-Core® Technology.

hplc columns for small molecule analysis

From an ultra-fast separation of a few compounds to a more complex natural product sample containing hundreds of analytes, HALO® columns offer an optimized solution for separation challenges.

lc column for biopharma solutions

Biopharmaceuticals are inherently more complex than small molecules. HALO® BioClass columns have been specifically designed to accomplish these bio-separation goals with a simplified and more effective solution.

hplc environmental applications

Solutions for other persistent, high environmental-impact contamination agents such as pesticides, mycotoxins, herbicides, and more all based upon HALO’s 15 years of innovative and trusted technology.

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