HALO® Technical Resources | HPLC Information & Applications

New Dimension in Chromatography - Halo^® 1.5

Application Notes

Conference Papers

Product Literature

Technical Documents

Enhanced Sensitivity for Intact Monoclonal Antibody Analysis via LCMS using a Novel UHPLC Column Design
Conference Paper

New 1.5 MM UHPLC Columns Enable Robust Separations with Increased Sensitivity and Solvent Savings
Conference Paper

Separation of Short and Long Chain Oligonucleotides through the Use of a Large Pore SPP Column
Conference Paper

Development of a Sensitive, High‐Resolution LCMS HILIC Method of the Oxidation of NIST mAb as an Alternate to Reverse Phase
Conference Paper

LC/MS HILIC Analysis for Glycosylation and Deamidation of Peptide and mAbs
Conference Paper

LC-MS Method Development and Column Screening for Pharmaceutical and Personal Care Products in the Environment
Conference Paper

Selection of HPLC and LC/MS Conditions for the Separation of Polar Compounds and Protein Modifications
Conference Paper

Rapid PFAS Analysis Using Fused-Core Technology
Conference Paper

Fast Screening of Oligo and Poly-Saccharides in Beer
Conference Paper

Optimizing Particle Pores for HPLC Separation of Verapamil and other Mid-Size Molecule
Conference Paper

Screening Mycotoxins on Sorghum Grain viaSuperficially Porous Particle Columns
Conference Paper

Applications of SPPS in Environmental Analysis
Conference Paper

AQ-C18-Official Pittcon 2019 Poster-1
Conference Paper

C30-Official Pittcon 2019 Poster-2
Conference Paper

Superficially Porous Particles with C30 Stationary Phase for High Resolution Separations
Conference Paper

The Importance of Superficially Porous Particles in Modernizing HPLC Methods
Conference Paper

Characterization of the Activity and Kinetics of Guanine Deaminase
Conference Paper

High Resolution Separation for Detailed LC/MS Analysis of mAb Disulfide Variants
Conference Paper

Advantages of Superficially Porous Particles (SPP) for Faster HPLC and UHPLC Separations
Conference Paper

A Superficially Porous Particle (SPP) C30 Phase Designed for High Speed HPLC Applications
Conference Paper

Wide Pore Superficially Porous Particles with Various Bonded Phases For High Resolution Protein Chromatography
Conference Paper

Probes-Official Pittcon 2019 Poster-3
Conference Paper

Selectivity Manipulation for LC/MS Analysis of Protein Variants
Conference Paper

LC/MS Method for Analysis of Guanine Deaminase: Activity, Kinetics and Effects of Inhibitors
Conference Paper

EAS 2018 All You Wanted to Know about Method Development and Transfer but Were Afraid to Ask
Conference Paper

EAS 2018 New RP SPP Columns with Alternate Selectivity
Conference Paper

EAS 2018 Optimizing HPLC Separation Performance for Mid-Size Molecules
Conference Paper

EAS 2018 Wide Pore SPP Bonded Phase
Conference Paper

High Performance Separations using 100% Aqueous Mobile Phase Compatible Superficially Porous Particle Columns Coupled with Mass Spectrometry
Conference Paper

A Diphenyl Bonded Phase On Wide Pore Superficially Porous Particles For Efficient Separations of Proteins
Conference Paper

LC/MS Method for the Analysis of Guanine Deaminase
Conference Paper

One Size Does Not Fit All: Exploring the Relationship Between Pore Size and Separation Efficiency
Conference Paper

Pittcon 2018 New Superficially Porous ParticleColumn Selectivity Choices for Improved Separations
Conference Paper

Pittcon 2018 – Column Pore Size – An Underutilized Variable for Optimizing HPLC Separation
Conference Paper

2017 ASMS ThP 601 High Efficiency Wide Pore SPPs for LC-MS of Larger Particles
Conference Paper

How to Avoid Mismatch Between Solutes and Column Pores for Optimum HPLC Performance
Conference Paper

Superficially Porous Particles with Polar C18 Selectivity
Conference Paper

An Effective Method Development Strategy Using FUSED-CORE Columns
Conference Paper

HPLC 2017 Improving Biomolecule Separations with Superficially Porous Particles of Silica
Conference Paper

Improve HPLC Separations by Carefully Matching Column Pore-Size to Solute-Size MCF 2017
Conference Paper

ISPPP 2017 Comparison of Phenyl- and C18 Bonded Phases with Peptide Mixtures
Conference Paper

ISPPP 2017 High Efficiency Wide Pore SPPs for LC-MS of Larger Proteins
Conference Paper

Pittcon 2017 – Developing Methods When C18 Does Not Work
Conference Paper

EAS 2016 Impact of Pore Exclusion on RP-HPLC Column Performance
Conference Paper

EAS 2016 Peptide Mapping Analyses Using Different Mobile Phase Additives
Conference Paper

ISPPP 2016 LC-MS of mAb Structure Utilizing HALO BioClass Fused-Core Particles
Conference Paper

EAS 2015 LCMS Analysis of Monoclonal Antibody Structure Utilizing HALO BioClass Fused-Core Particles Multilevel Analysis for Proteins and Glycovariants
Conference Paper

HPLC 2015 Performance Features of 2 um Superficially Porous Particle Columns
Conference Paper

ISPPP 2015 Rapid and Specific HILIC Method to Assay Guanine Deaminase and Application to Characterize the Brain Enzyme
Conference Paper

ASMS 2015 – Prediction of Peptide RT in HILIC Poster
Conference Paper

Pittcon 2015 – Alternatives to Sub 2-micron UHPLC Columns
Conference Paper

2017 ASMS ThP 539 HILIC LC-MS Analytical Approach for ID of Protein Deamidation and Isomerization Modifications
Conference Paper

HPLC_2016_Improving Protein Separations
Conference Paper

ASMS 2016 High Resolution Separations for Protein LC MS
Conference Paper

ASMS 2015 Utilization of an Isotopically Labelled Glycoprotein Internal Standard to Enable Comparison of Glycan Quantitation
Conference Paper

ASMS 2015 Improving Protein LC-MS Analysis
Conference Paper

Characterization of Guanine Deaminase
Conference Paper