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New Dimension in Chromatography - Halo® 1.5

LCGC webinar

Basic Analyte Blues? Elevate Your Separations of Basic Compounds at High pH Using New Column Chemistry

Registration link: 


Airing 1: Thursday, May 30, 2024, 11am Eastern Daylight Time | 12pm Central Daylight Time | 8am Pacific Daylight Time

Airing 2: Friday, May 31, 2024 11am Chinese Standard Time | 12pm Japan Standard Time | 1pm Australian Eastern Standard Time

Presenter:  Stephanie A. Schuster, Ph.D. Senior Technical Support Scientist, Advanced Materials Technology

Event Overview:

LC and LCMS methods run at elevated pH show advantages in terms of retention and peak shape symmetry for basic analytes. A new high pH stable silica phase designed on superficially porous particle technology enables separation methods using both elevated pH and temperature. Comparative stability data and application examples showing how chromatography improves when moving from low pH to high pH conditions will be presented for small molecule analytes and oligonucleotides.

Key Learning Objectives:

  • Improve the peak shape and retention of basic compounds by using a high pH stable SPP column.
  • Understand the advantages of pH as a method development leveler.
  • Learn about the column options for analyzing basic analytes based upon selected pH.

Who Should Attend:

  • Scientists developing LC and LCMS methods
  • Lab managers
  • Chromatographers
  • QA/QC managers
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