Designed for separation of novel and legacy short chain and long chain PFAS compounds containing branched and linear isomers, along with EPA methodology requirements in mind, HALO® PFAS offers a holistic solution.
With both a PFAS specific delay column optimized to prevent background PFAS contamination from interfering with the sample results and an analytical column for PFAS sample separation and detection, the HALO® PFAS solution delivers excellent selectivity, peak shape and necessary retention to perform fast, high resolution separations in EPA methods 1633, 537.1, 533, 8327 and emerging ultra short chain testing.
A PFAS specific delay column is optimized to prevent background PFAS contamination from interfering with the sample results. HALO® PFAS solution delivers excellent selectivity, peak shape and necessary retention to perform fast, high-resolution separations.
Available Phases
High speed separation of 33 PFAS species found in EPA 537.1, EPA 533, and EPA 8327, completed in under 5 minutes using PFAS C18 (2.7 um).

The latest EPA 1633 method includes 40 PFAS compounds across nine different compound classes (including linear and branched isomers) using a reversed phase C18 column along with an analytical delay column. The figure below represents a fortified soil sample that has been spiked with each PFAS standard at 5 ppb following solid phase extraction.

The use of a HALO® PFAS PCS Phenyl-Hexyl column, in combination with a HALO® PFAS Delay Column,
enabled robust retention and resolution of ultra short to long chain PFAS analytes. The PCS (Positively Charged
Surface) ligand provides enhanced interaction with highly polar, short chain PFAS—resulting in significantly improved retention compared to conventional C18 phases.

HALO® PFAS Delay is an application assured column solution. The delay column is used to prevent background PFAS contamination from interfering with the PFAS of interest that are separated with the analytical column.