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New Dimension in Chromatography - Halo® 1.5

Improving Small Molecule Analysis: Increasing the Sensitivity While Reducing Solvent Consumption by Using 1.5 mm ID Columns

Improving Small Molecule Analysis: Increasing the Sensitivity While Reducing Solvent Consumption by Using 1.5 mm ID Columns

AUTHOR: Stephanie Schuster, Ph.D., Senior Technical Support Scientist ABSTRACT The new HALO® 1.5 mm ID columns offer an alternative to analytical and narrow bore columns for greater separation performance with the benefits of increased sensitivity, reduced solvent consumption/reduced waste disposal costs,…

A Novel Screening Approach for Comparing LC-MS Reversed-Phase and HILIC Methods for Separations in Biological Matrices Using Amino Acid Examples

A Novel Screening Approach for Comparing LC-MS Reversed-Phase and HILIC Methods for Separations in Biological Matrices Using Amino Acid Examples

AUTHOR: Conner McHale, Technical Support Specialist and Taylor Harmon, Ph.D., R&D Scientist ABSTRACT Metabolomic analyses are utilized in various avenues of clinical research, including drug discovery, disease characterization, and pharmacodynamic evaluation. Metabolites are often studied via liquid chromatography-mass spectrometry (LC-MS)…

Water and Fat-Soluble Vitamin Separations Using the HALO® C18 and AQ-C18 Phases

Water and Fat-Soluble Vitamin Separations Using the HALO® C18 and AQ-C18 Phases

AUTHOR: Peter Pellegrinelli, M.S., Applications Specialist ABSTRACT Vitamins are a crucial nutrient to humans and animals alike. In order for people to live healthy lives they need the right nutrients to enable these healthy conditions. Today, people are more conscious…

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