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New Dimension in Chromatography - Halo® 1.5

LC Chromatography Troubleshooting

LC Chromatography Troubleshooting

Introduction High-pressure liquid chromatography (HPLC) is a benchmark technique used in laboratories across the world. However, even experienced analysts that are familiar with HPLC concepts and principles can fall victim to chromatographic pitfalls that arise. Some common issues include misshapen…

New Amino Acid White Paper

New Amino Acid White Paper

Amino acid analysis (AAA) is an important technique for determining the quantity of amino acids in a sample. In the biopharmaceutical industry, amino acid analysis has become an important tool in quantifying amino acid content in both feed and spent…

A Novel Screening Approach for Comparing LC-MS Reversed-Phase and HILIC Methods for Separations in Biological Matrices Using Amino Acid Examples

A Novel Screening Approach for Comparing LC-MS Reversed-Phase and HILIC Methods for Separations in Biological Matrices Using Amino Acid Examples

AUTHOR: Conner McHale, Technical Support Specialist and Taylor Harmon, Ph.D., R&D Scientist ABSTRACT Metabolomic analyses are utilized in various avenues of clinical research, including drug discovery, disease characterization, and pharmacodynamic evaluation. Metabolites are often studied via liquid chromatography-mass spectrometry (LC-MS)…

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