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New Dimension in Chromatography - Halo® 1.5

New USP  Guideline White Paper

New USP Guideline White Paper

June 7, 2023
Elizabeth Langois

The guidelines in USP Chapter <621> were recently updated to allow changes to gradient methods in terms of particle size and column dimensions with verification instead of revalidation. This change enables laboratories to benefit from modern column particle sizes and…

A Novel Screening Approach for Comparing LC-MS Reversed-Phase and HILIC Methods for Separations in Biological Matrices Using Amino Acid Examples

A Novel Screening Approach for Comparing LC-MS Reversed-Phase and HILIC Methods for Separations in Biological Matrices Using Amino Acid Examples

May 11, 2023
Emma Marzullo

AUTHOR: Conner McHale, Technical Support Specialist and Taylor Harmon, Ph.D., R&D Scientist ABSTRACT Metabolomic analyses are utilized in various avenues of clinical research, including drug discovery, disease characterization, and pharmacodynamic evaluation. Metabolites are often studied via liquid chromatography-mass spectrometry (LC-MS)…

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