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HALO® Columns for Chromatography Separations
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New Dimension in Chromatography - Halo® 1.5

Technical Documents

Application Notes
Conference Papers
Product Literature
Technical Documents
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CLEAR FILTERS
Improved Bioseparations with a Novel Charged Surface Superficially Porous Silica Column
Conference Paper
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HPLC Approaches to Improve Peak Shape for Basic Analytes
Conference Paper
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LC/MS Approaches for Analysis of PFAS Short and Long Chain Mixtures
Conference Paper
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Current LC/MS Approaches for PFAS Analysis with Short and Long Chain Mixtures
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Improving Chromatography for Basic Analytes Using Positive Charge Surface Material
Conference Paper
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Method Development Approach to Separating Oligonucleotides Under UV and MS Detection
Conference Paper
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Enhancing LC and LC-MS Separations of Basic Compounds with Novel High pH Stable SPP Columns
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New Column Technology for Improved Oligonucleotide Separations
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Improving Short Chain PFAS Analysis Using Reversed Phase Conditions
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Evaluation of Positively Charged Surface Stationary Phases for Improved Chromatographic Separations of Basic Analytes in Small Molecules and Peptides
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Method Development Approach to Separating Oligonucleotides with Superficially Porous Particle Columns
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Evaluation of Positively Charged Surface Phenyl-Hexyl Stationary Phase for Separation of Basic Small Molecule Drugs
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Demonstration of the Utility of a 1.5 mm ID UHPLC column for Pesticide Analysis Using the Multi-Analyte Method
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Evaluation of Positively Charged Surface Phenyl-Hexyl Stationary Phase for Separation of Basic Small Molecule Drugs
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Charged-Surface Stationary Phase Improves Peptide Separations in Low Ionic Strength Mobile Phases
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HPLC Separation Improvement for Short Chain PFAS
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Positively Charged Surface Chemistry for Biological Separations
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Small Molecule HPLC Method Optimization using Positive Charge Surface
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Drugs of Abuse and Metabolite Screening Using High Efficiency LC Columns
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Impact of Using 1.5 mm ID Column and Various Stationary Phases on LCMS Pesticide Screening Analysis
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Modernizing USP Methods According to <621> with Superficially Porous Particle Columns
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Increased Efficiency of Protein and Peptide Separations by Varying Particle Size, Column Dimension, and Pore Size of Superficially Porous Particle Columns
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Small Molecule HPLC Method Optimization Using an Acidic, Basic, and Neutral Panel and Superficially Porous Particles
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RPLC-MS analytical method for the separation of all hydroxyproline isomers and application to different collagen hydrolysates
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Implementing 1.5 mm inner diameter columns into LC-MS bottom-up proteomic workflows
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Increasing Efficiency of Peptide Separations by Decreasing Particle Size and Column Dimension
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A Novel Screening Approach for Comparing LC-MS Reversed-Phase and HILIC Methods for Separations in Biological Matrices Using Amino Acid Examples
Conference Paper
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Opportunities for Developing Improved Separation Methods with Modern UHPLC Instruments
Conference Paper
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Comparison of LC-MS Pesticide Screening Results Using Different Reversed-Phase Superficially Porous Columns
Conference Paper
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Cannabinoid Separation Using LPH-C18
Conference Paper
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Optimizing Older UHPLC Systems for Use with New, Smaller ID Columns
Conference Paper
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A Simple Method for Predicting HPLC Selectivity in Ternary Reversed-Phase Solvent Systems
Conference Paper
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Monoclonal Antibody Analysis with Compact Capillary LC Instrumentation 
Conference Paper
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Enhanced Sensitivity for Peptide and Protein Applications Using the 1.5mm ID Column
Conference Paper
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LPH-C18: A C18 Column Alternative
Conference Paper
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Exploring the Improvements Enabled by 1.5 mm ID UHPLC SPP Columns
Conference Paper
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Implementing 1.5 mm ID Columns into Analytical Workflows
Conference Paper
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Enhanced Sensitivity for Intact Monoclonal Antibody Analysis via LCMS using a Novel UHPLC Column Design
Conference Paper
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New 1.5 MM UHPLC Columns Enable Robust Separations with Increased Sensitivity and Solvent Savings
Conference Paper
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Separation of Short and Long Chain Oligonucleotides through the Use of a Large Pore SPP Column
Conference Paper
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Development of a Sensitive, High‐Resolution LCMS HILIC Method of the Oxidation of NIST mAb as an Alternate to Reverse Phase
Conference Paper
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LC/MS HILIC Analysis for Glycosylation and Deamidation of Peptide and mAbs
Conference Paper
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LC-MS Method Development and Column Screening for Pharmaceutical and Personal Care Products in the Environment
Conference Paper
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Selection of HPLC and LC/MS Conditions for the Separation of Polar Compounds and Protein Modifications
Conference Paper
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Rapid PFAS Analysis Using Fused-Core Technology
Conference Paper
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Fast Screening of Oligo and Poly-Saccharides in Beer
Conference Paper
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Optimizing Particle Pores for HPLC Separation of Verapamil and other Mid-Size Molecule
Conference Paper
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Screening Mycotoxins on Sorghum Grain viaSuperficially Porous Particle Columns
Conference Paper
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Applications of SPPS in Environmental Analysis
Conference Paper
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AQ-C18-Official Pittcon 2019 Poster-1
Conference Paper
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C30-Official Pittcon 2019 Poster-2
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Superficially Porous Particles with C30 Stationary Phase for High Resolution Separations
Conference Paper
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The Importance of Superficially Porous Particles in Modernizing HPLC Methods
Conference Paper
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Characterization of the Activity and Kinetics of Guanine Deaminase
Conference Paper
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High Resolution Separation for Detailed LC/MS Analysis of mAb Disulfide Variants
Conference Paper
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Advantages of Superficially Porous Particles (SPP) for Faster HPLC and UHPLC Separations
Conference Paper
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A Superficially Porous Particle (SPP) C30 Phase Designed for High Speed HPLC Applications
Conference Paper
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Wide Pore Superficially Porous Particles with Various Bonded Phases For High Resolution Protein Chromatography
Conference Paper
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Probes-Official Pittcon 2019 Poster-3
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Selectivity Manipulation for LC/MS Analysis of Protein Variants
Conference Paper
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LC/MS Method for Analysis of Guanine Deaminase: Activity, Kinetics and Effects of Inhibitors
Conference Paper
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EAS 2018 All You Wanted to Know about Method Development and Transfer but Were Afraid to Ask
Conference Paper
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EAS 2018 New RP SPP Columns with Alternate Selectivity
Conference Paper
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EAS 2018 Optimizing HPLC Separation Performance for Mid-Size Molecules
Conference Paper
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EAS 2018 Wide Pore SPP Bonded Phase
Conference Paper
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High Performance Separations using 100% Aqueous Mobile Phase Compatible Superficially Porous Particle Columns Coupled with Mass Spectrometry
Conference Paper
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A Diphenyl Bonded Phase On Wide Pore Superficially Porous Particles For Efficient Separations of Proteins
Conference Paper
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LC/MS Method for the Analysis of Guanine Deaminase
Conference Paper
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One Size Does Not Fit All: Exploring the Relationship Between Pore Size and Separation Efficiency
Conference Paper
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Pittcon 2018 New Superficially Porous ParticleColumn Selectivity Choices for Improved Separations
Conference Paper
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Pittcon 2018 – Column Pore Size – An Underutilized Variable for Optimizing HPLC Separation
Conference Paper
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2017 ASMS ThP 601 High Efficiency Wide Pore SPPs for LC-MS of Larger Particles
Conference Paper
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How to Avoid Mismatch Between Solutes and Column Pores for Optimum HPLC Performance
Conference Paper
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Superficially Porous Particles with Polar C18 Selectivity
Conference Paper
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An Effective Method Development Strategy Using FUSED-CORE Columns
Conference Paper
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HPLC 2017 Improving Biomolecule Separations with Superficially Porous Particles of Silica
Conference Paper
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Improve HPLC Separations by Carefully Matching Column Pore-Size to Solute-Size MCF 2017
Conference Paper
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ISPPP 2017 Comparison of Phenyl- and C18 Bonded Phases with Peptide Mixtures
Conference Paper
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ISPPP 2017 High Efficiency Wide Pore SPPs for LC-MS of Larger Proteins
Conference Paper
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Pittcon 2017 – Developing Methods When C18 Does Not Work
Conference Paper
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EAS 2016 Impact of Pore Exclusion on RP-HPLC Column Performance
Conference Paper
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EAS 2016 Peptide Mapping Analyses Using Different Mobile Phase Additives
Conference Paper
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ISPPP 2016 LC-MS of mAb Structure Utilizing HALO BioClass Fused-Core Particles
Conference Paper
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EAS 2015 LCMS Analysis of Monoclonal Antibody Structure Utilizing HALO BioClass Fused-Core Particles Multilevel Analysis for Proteins and Glycovariants
Conference Paper
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HPLC 2015 Performance Features of 2 um Superficially Porous Particle Columns
Conference Paper
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ISPPP 2015 Rapid and Specific HILIC Method to Assay Guanine Deaminase and Application to Characterize the Brain Enzyme
Conference Paper
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ASMS 2015 – Prediction of Peptide RT in HILIC Poster
Conference Paper
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Pittcon 2015 – Alternatives to Sub 2-micron UHPLC Columns
Conference Paper
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2017 ASMS ThP 539 HILIC LC-MS Analytical Approach for ID of Protein Deamidation and Isomerization Modifications
Conference Paper
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HPLC_2016_Improving Protein Separations
Conference Paper
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ASMS 2016 High Resolution Separations for Protein LC MS
Conference Paper
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ASMS 2015 Utilization of an Isotopically Labelled Glycoprotein Internal Standard to Enable Comparison of Glycan Quantitation
Conference Paper
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ASMS 2015 Improving Protein LC-MS Analysis
Conference Paper
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Characterization of Guanine Deaminase
Conference Paper
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